top of page

Academic Publications

Research Investigations

 

Singh JP, Patki SA, Melinkeri RR. Serum -ascitic albumin concentration gradient; a distinctive approach to diagnostic evaluation of ascites. Medical Journal of Western India 1988; 16:21-25.

 

Patki P, Singh JP, Gokhale SV, Bulakh PM. Efficacy of potassium and magnesium in essential hypertension; a double blind, placebo controlled, cross over study. British Medical Journal 1990; 301: 521-523.

 

Gulati RB, Singh JP, Sreenivas CG. A Clinico-electrocardiographic study of right ventricular infarctions in patients with inferior wall myocardial infarctions. Journal of Inernational Medical Sciences Academy 1992; 5: 19-24.

 

Dalvi BV, Kerkar PG, Vora A, Singh JP. What should be called a brisk Y descent. Journal of Postgraduate Medicine 1992; 38: 171-74.

 

Gulati RB, Singh JP, Gulati JM, Makhale CN. Clinical and angiographic observations in unstable angina. Journal of International Medical Sciences Academy 1993; 6: 61-65.

 

Singh JP, Sleight P, Johnston J, Bird R, Ryder K, Hart G. Abnormal rate adaptation of the QT interval is associated with hypertensive left ventricular hypertrophy. Journal of American College of Cardiology 1997;29:778-84.

 

Singh JP, Johnston J, Sleight P, Marinho M, Casadei B, Hart G. Circadian variations and waking hour dynamics of the QT interval. Annals of Noninvasive Electrocardiology 1997;2:242-253.

 

Kardos A, Long V, Bryant J, Singh JP, Sleight P, Casadei B. Lipophilic versus hydrophilic beta(1) blockers and the cardiac sympatho-vagal balance during stress and daily activity in patients after acute myocardial. Heart, 1998 ;79:153-60.

 

Roukema G, Singh JP , Meijs, Carvalho C; Hart G. Effect of exercise-induced ischemia on QT interval dispersion. Am Heart J, 1998;135:88-92.

 

Singh JP, Musialek P, Sleight ,; Davey P, Marinho M, Hart G. Effect of atenolol or metoprolol on waking hour dynamics of the QT interval in myocardial infarction. Am J Cardiol, 1998;81:924-6.

 

Singh JP, Larson MG; Tsuji H, Evans JC, O'Donnell CJ, Levy D. Reduced heart rate variability and new-onset hypertension: insights into pathogenesis of hypertension: the Framingham Heart Study. Hypertension, 1998; 32:293-7.

 

Singh JP, Evans JC, Levy D, Larson MG, Freed LA, Fuller DL, Lehman B, Benjamin EJ. Prevalence of aortic, mitral and tricuspid regurgitation in a population based cohort. Am J Cardiol, 1999;83:897-902.

 

Singh JP; Larson MG; Manolio TA; O'Donnell CJ; Lauer MA; Levy D. Blood pressure response to treadmill testing as a risk factor for new onset hypertension : the Framingham Heart Study. Circulation, 1999;99:1831-1836.

 

Singh JP; Larson MG; O'Donnell CJ; Tsuji H; Levy D. Heritability of heart rate variability: the Framingham Heart Study. Circulation, 1999;99: 2251-2254.

 

Meijs M, Roukema G, Singh JP. Inter-lead differences in QT interval dynamics. American Heart Journal; 2000; 139(3):558. (Original Research Letter)

 

Singh JP, Larson MG, O'Donnell CJ, Tsuji H, Wilson PW, Lloyd-Jones D, Levy D. Hyperglycemia is asscociated with reduced heart rate variability: The Framingham Heart Study. Am J Cardiol,2000;86:309-312 

 

Research 88-2000
2001 - 2010

Singh JP, Larson MG, O'Donnell CJ, Tsuji H, Corey D, Levy D. Genome scan linkage results of heart rate variability. Am J Cardiol 2002;90:1290-1293.

 

Singh JP, Larson MG, Tsuji H, Corey, D, Levy D, Benjamin E. Is baseline autonomic tone associated with new onset atrial fibrillation. Annals of Noninvasive electrocardiology 2004 9(3):215-220.

 

Heist EK, Doshi SK, Singh JP, Reddy VR, Ruskin JN, Mansour M. Atrial Flutter ablation in cardiac transplantation patients. Journal of Cardiovascular Electrophysiology; 2004:15:1-5.

 

Whang W, Albert CM, Sears SF Jr, Lampert R, Conti JB, Wang PJ, Singh JP, Ruskin JN, Muller JE, Mittleman MA; TOVA Study Investigators. Depression as a predictor for appropriate shocks among patients with implantable cardioverter-defibrillators Results from the Triggers of Ventricular Arrhythmias (TOVA) study. J Am Coll Cardiol. 2005;45(7):1090-5

 

Singh JP, Hall WJ, McNitt S, Daubert JP, Zareba W, Ruskin JN, Moss AJ. Factors influencing appropriate firing of the implanted defibrillator for ventricular tachycardia/fibrillation: findings from the Multicenter Automatic Defibrillator Implantation Trial II. J Am Coll Cardiol 2005 46(9):1712-20

 

Singh JP, Houser S, Heist EK, Ruskin JN. Coronary venous anatomy: a segmental approach to aid cardiac resynchronisation therapy.  J Am Coll Cardiol . 2005;46:68-74 (Viewpoint with original data presented).

 

Heist EK, Fan D, Mela T, Arzola-Castaner D, Reddy VR, Mansour M , Picard M, Ruskin JN and Singh JP.  Radiographic LV-RV lead inter-lead distance predicts the acute hemodynamic response to cardiac resynchronization therapy. . Am J Cardiol. 2005;96:685-90.

 

Singh JP and Ruskin JN. Cardiac Resynchronization Therapy: The MGH Experience. Annals Noninvasive Electrocardiology 2005; 10:44-54 (original research included)

 

Mansour M, Reddy VY, Singh JP, Mela T, Rasche V, Ruskin JN. Three dimensional reconstruction of the coronary sinus using rotational angiography. J Cardiovasc Electrophysiol. 2005 ;16:675-6

 

Arzola-Castaner D, Taub C, Heist EK, Fan D, Mela T, Haelewyn K , Picard M, Ruskin JN and Singh JP.  Left ventricular lead proximity to an akinetic segment and impact on outcome of cardiac resynchronization therapy. J Cardiovasc Electrophysiol, 2006; 17; 623-627

 

Heist EK, Taub C, Fan D, Mela T, Arzola-Castaner D, Reddy VR, Mansour M , Picard M, Ruskin JN and Singh JP.  Usefulness of a Novel Response Score to Predict Hemodynamic and Clinical Outcome from Cardiac Resynchronization Therapy. Am J Cardiol. 2006;97:1732-6.

 

Singh JP, Fan D, Heist EK, Alabiad CR, Taub C, Reddy V, Mansour M, Picard MH, Ruskin JN, Mela T. Left ventricular lead electrical delay predicts response to cardiac resynchronization therapy Heart Rhythm. 2006 Nov;3(11):1285-92.

 

Singh JP, Heist, EK, Ruskin JN and Harthorne W. Dial-in-CRT: overcoming the constraints of the coronary venous anatomy. J Interv Card Electrophysiol 2006, 17:51-58. (Viewpoint with original data presented)

 

Danik SB, Mansour M, Singh JP, Reddy VY, Ellinor PT, Milan D, Heist EK, D’Avila A, Ruskin JN, Mela T.  Increased incidence of subacute lead perforation noted with one implantable cardioverter-defibrillator. Heart Rhythm. 2007 (4):439-42.

 

Aryana A, d'Avila A, Heist EK, Mela T, Singh JP, Ruskin JN, Reddy VY. Remote magnetic navigation to guide endocardial and epicardial catheter mapping of scar-related ventricular tachycardia. Circulation. 2007; 115(10):1191-200.

 

Heist EK, Chevalier J, Holmvang G, Singh JP, Ellinor PT, Milan DJ, D’Avila A, Mela T, Ruskin JN, Mansour M. Factors affecting error in integration of electroanatomic mapping with CT and MR imaging during catheter ablation of atrial fibrillation. J Interv Card Electrophysiol. 2006;17(1):21-7.

 

Stern J, Heist EK, Chung J, Murray L, Mela T, Ruskin J, Singh JP. Elevated Pulmonary Artery Systolic Pressure is Associated with an Adverse Clinical Outcome in Patients Receiving Cardiac Resynchronization Therapy. PACE, 2007;30(5):603-7.

 

Tournoux F, Fan D, Chen A, Chaput M, Heist EK, Mansour MC, Mela TM, Ruskin J, Picard and Singh JP. Echocardiographic Measures of Acute Hemodynamic Response after Cardiac Resynchronization Therapy Predict Long-term Clinical Outcome. European Heart Journal, 2007;28(9):1143-8.

 

Tournoux F, Manzke R, Chan R, Jorge Solis, Chen A, Ruskin J, Picard M, Weyman, AE and Singh JP. Integrating Functional and Anatomical information to facilitate cardiac resynchronization therapy. PACE 2007; 30:1021-1022. (Original data presented)

 

Gilliam FR, Singh JP, Mullin CM, McGuire M, Chase KJ. Prognostic value of heart rate variability footprint and standard deviation of average 5-minute intrinsic R-R intervals for mortality in cardiac resynchronization therapy patients. J Electrocardiol 2007;40: 336-42.

 

Blendea D, Shah R, Nandigam V, Tournoux F, Zardkoohi O, Orencole M, Heist EK, Reddy, V, McPherson C, Ruskin J, Singh JP. Variability of Coronary Venous Anatomy in Patients Undergoing Cardiac Resynchronization Therapy: A High Speed Rotational Venography Study. Heart Rhythm 2007;(9):1155-62.

 

Blendea D, Mansour M, Shah RV, Nandigam V, Orencole M, Heist EK, Mela TM, Reddy, V, Manzke R, McPherson C, Ruskin J, Singh JP. Usefulness of High Speed Rotational Coronary Venous Angiography during Cardiac Resynchronization Therapy. Am J Cardiol. 2007;100:1561-5. 

 

Zardkoohi O, Murray L, Chung J, Heist EK, Mela T, Ruskin JN, and Singh JP. The Impact of Age and Gender on Cardiac Resynchronization Therapy Outcome. Pacing Clin Electrophysio. 2007;30:1344-8

 

Auricchio A, Sorgente A, Singh JP, Faltera F, Conca G, Siclari F and Moccetti T. Role of multislice computed tomography for preprocedural evaluation before revision of a chronically implanted transvenous left ventricular lead.Am J Cardiol. 2007;100:1566-70.

 

Das S, Neuzil P, Albert CM, D’Avila, Mansour M, Mela T, Singh JP, Patton K, Ruskin JN, Reddy VY. Catheter ablation of peri-AV nodal atrial tachycardia from the noncoronary cusp of the aortic valve.J Cardiovasc Electrophysiol. 2008 ;19(3):231-7. 

 

Patel A, Singh JP and Ruskin JN. The role of implantable cardioverter defibrillators in methadone-induced long QT syndrome. Am J Cardiol. 2008 Jan 15;101(2):209-11.

 

Upadhyay G, Choudhry N, Auricchio A Ruskin JN and Singh JP. Cardiac Resynchronization in Patients with Atrial Fibrillation: a Meta-analysis of Prospective Cohort Studies’. J Am Coll Cardiol 2008;52 1239-1246.

 

Sorgente A, Truoung QA, Conca C, Singh JP, Hoffman U, Faltera FF, Klersy C, Bhatia R, pedrazzini GB, Pasotti E, Moccetti T, Auricchio A. Influence of left atrial and ventricular volumes on the relation between mitral valve annulus and coronary sinus. Am J Cardiol. 2008 Oct 1;102(7):890-6.

 

Ajijola, O, Nandigam, V, De, GW, Chabner B, Ruskin, J and Singh JP. Usefulness of cardiac resynchronization therapy in the management of Doxorubicin-induced cardiomyopathy Am J Cardiol. 2008;101(9):1371-2.

 

Patel A, D’Avila A, Neuzil P, Mela, T, Kim SJ, Singh JP, Ruskin JN, Reddy V. Atrial Tachycardia after Ablation of Persistent Atrial Fibrillation: Identification of the Critical Isthmus with a Combination of Multielectrode Activation Mapping and Targeted Entrainment Mapping. Circulation, Arrhythmia Electrophysiol 2008:1:14-22.

 

Truong QA, Hoffman U, Singh JP. Potential Uses of CT for Management of Heart Failure Patients with Dyssynchrony. Crit Pathw Cardiol. 2008 ;7(3):185-90.

 

Truong QA, Singh JP, Cannon CP, Aurrichio A, Faletra F, Sorgente A, Conca C, Moccetti T, Handschumacher M, Brady T, Hoffman U. Quantitative Analysis of Intraventricular Dyssynchrony Using Wall Thickness: Initial Description of a Novel Method by Multi-Detector Computed Tomography. J Am Coll of Cardio. Imag. 2008,1:772-781.

 

Solis J, McCarty D, Levine RA, Handschumacher MD, Fernandez-Friera L, Chen-Tournoux A, Mont L, Vidal B, Singh JP, Brugada J, Picard MH, Sitges M, Hung J. Mechanism of decrease in mitral regurgitation after cardiac resynchronization therapy: optimization of the force-balance relationship. Circ Cardiovasc Imaging. 2009 Nov;2(6):444-50. 

 

Singh JP, Rosenthal LS, Hranitzky PM, Berg KC, Mullin CM, Thackeray L, Kaplan A. Device Diagnostics and Long Term Clinical Outcome in Patients Receiving Cardiac Resynchronization Therapy. Europace. 2009 Dec;11(12):1647-53. 

 

Blendea D, Heist EK, Das S, Danik SB, Barrett C, Mela T, Ruskin JN, Singh JP. Impact of tricuspid regurgitation and prior coronary bypass surgery on the geometry of the coronary sinus. J Cardiovasc Electrophysiol. 2010 Apr;21(4):436-40. 

 

Tournoux F, Chan RC, Manzke R, Handschumacher BA, Chen-Tournoux A, Gerard O, Solis-Martin J, Truong QA, Heist EK, Alain P, Ruskin JN, Weyman A, Picard M, Singh JP. Integrating Functional and Anatomical Information to guide Cardiac resynchronization Therapy. Eur J Heart Fail. 2010 Jan;12(1):52-7. 

 

Ryu K, D’Avila A, Heist EK, Rosenberg SP, Chou JC, Yang M, Singh JP. Simultaneous Electrical and Mechanical Mapping using 3D Cardiac Mapping System: Novel Approach for Optimal cardiac Resynchronization Therapy, J Cardiovasc Electrophysiol. 2010 Feb;21(2):219-22.

 

Merchant FM, Heist EK, McCart D, Kumar P, Das, S, Blendea D, Ellinor P, Mela T, Picard M, Ruskin JN, Singh JP. Impact of Segmental Left Ventricle Lead Position on Cardiac Resynchronization Therapy Outcomes. Heart Rhythm. 2010 May;7(5):639-44.

 

Merchant FM, Heist EK, Nandigam KV, Mulligan LJ, Blendea D, Riedl L, McCarty D, Orencole M, Picard MH, Ruskin JN, Singh JP. Radiographic inter-lead distance and left ventricular lead electrical delay predict anatomic reverse remodeling during cardiac resynchronization therapy. Pacing Clin Electrophysiol. 2010 Jan 8.

 

Ajijola OA, Macklin EA, Moore SA, McCarty D, Bischoff KE, Heist EK, Picard M, Ruskin JN, Dec GW, Singh JP. Inpatient vs. elective outpatient cardiac resynchronization therapy device implantation and long-term clinical outcome. Europace. 2010 Dec;12(12):1745-9. 

 

Kulik A, Singh JP, Avorn J, Choudhry N. Title: Association Between Statin Use and the Incidence of Atrial Fibrillation Following Hospitalization for Coronary Artery Disease. Am J Cardiol. 2010 Jun 15;105(12):1655-60.

 

Lubitz SA, Leong-Sit P, Fine N, Kramer D, Singh JP, Ellinor PT. Effectiveness of Cardiac Resynchronization Therapy in Mild Congestive Heart Failure: Systematic Review and Meta-Analysis of Randomized Trials. Eur J Heart Failure 2010; Apr;12(4):360-6

 

Ellenbogen KA, Gold MR, Meyer TE, Fernndez Lozano I, Mittal S, Waggoner AD, Lemke B, Singh JP, Spinale FG, Van Eyk JE, Whitehill J, Weiner S, Bedi M, Rapkin  J, Stein KM. Primary results from the SmartDelay determined AV optimization: a comparison to other AV delay methods used in cardiac resynchronization therapy (SMART-AV) trial: a randomized trial comparing empirical, echocardiography-guided, and algorithmic atrioventricular delay programming in cardiac resynchronization therapy. Circulation. 2010 Dec 21;122(25):2660-8.

2011 - 2015

Troughton RW, Ritzema J, Eigler NL, Melton IC, Krum H, Adamson PB, Kar S, Shah PK, Whiting JS, Heywood JT, Rosero S, Singh JP, Saxon L, Matthews R, Crozier IG, Abraham WT; HOMEOSTASIS Investigators. Direct left atrial pressure monitoring in severe heart failure: long-term sensor performance. J Cardiovasc Transl Res. 2011 Feb;4(1):3-13.

 

Chatterjee AN, Gallagher JJ, Poku J, Akar J, Mitchell K, Singh JP on behalf of the TRIAGE Investigators. Telemonitoring in Patients with CHF and Indication for ICD-Cardiac Resynchronization Therapy. The Journal of Innovations in Cardiac Rhythm Management, 2 (2011), 347–352

 

Kumar P, Blendea D, Nandigam V, Moore SA, Heist EK, Singh JP. Assessment of the post-implant final left ventricular lead position: a comparative study between radiographic and angiographic modalities. J Interv Card Electrophysiol. 2010;29(1):17-22.

 

Singh JP, Klein HU, Huang DT, Reek S, Kuniss M, Quesada A, Barshenet A, Cannom D, Goldenberg I, McNitt S, Daubert J, Zareba W, Moss AJ. Left Ventricular Lead Position and Clinical Outcome in the  MADIT-CRT Trial. Circulation 2011 Mar 22;123(11):1159-66.

 

Tournoux F, Singh JP, Chan RC, Chen-Tournoux A, McCarty D, Manzke R, Ruskin JN, Semigran M, Heist EK, Moore S, Picard MH, Weyman AE. Absence of left ventricular apical rocking and atrial-ventricular dyssynchrony predicts non-response to cardiac resynchronization therapy. Eur Heart J Cardiovasc Imaging. 2012 Jan;13(1):86-94.

 

Gold MR, Birgersdotter-Green U, Singh JP, Ellenbogen KA, Yu Y, Meyer TE, Seth  M, Tchou PJ. The relationship between ventricular electrical delay and left ventricular remodelling with cardiac resynchronization therapy. Eur Heart J. 2011 Oct;32(20):2516-24. 

 

Altman RK, McCarty D, Chen-Tournoux AA, Tournoux FB, Riedl L, Orencole M, Park MY, Picard MH, Singh JP. Usefulness of low-dose dobutamine echocardiography to predict response and outcome in patients undergoing cardiac resynchronization therapy. Am J Cardiol. 2011 Jul 15;108(2):252-7.

 

Weiss EH, Merchant FM, d'Avila A, Foley L, Reddy VY, Singh JP, Mela T, Ruskin JN, Armoundas AA. A novel lead configuration for optimal spatio-temporal detection of intracardiac repolarization alternans. Circ Arrhythm Electrophysiol. 2011 Jun 1;4(3):407-17. 

 

Refaat M, Mansour M, Singh JP, Ruskin J, Heist EK. Electrocardiographic characteristics in right ventricular vs biventricular pacing in patients with paced right bundle-branch block QRS pattern. J Electrocardiol. 2011 Mar-Apr;44(2):289-95.

 

Hayward RM, Upadhyay GA, Mela T, Ellinor PT, Barrett CD, Heist EK, Verma A, Choudhry NK, Singh JP. Pulmonary vein isolation with complex fractionated atrial  electrogram ablation for paroxysmal and nonparoxysmal atrial fibrillation: A meta-analysis. Heart Rhythm. 2011 Jul;8(7):994-1000. 

 

Chatterjee NA, Upadhyay GA, Ellenbogen KA, McAlister FA, Choudhry NK, Singh JPAtrioventricular Nodal Ablation in Atrial Fibrillation: A Meta-analysis and Systematic Review. Circ Arrhythm Electrophysiol. 2012 Feb 1;5(1):68-76.

 

Singh JP, Kulik, A, Levin, R, Ellinor PT, Ruskin JN and Choudhry NK. Renin-Angiotensin-System Modulators and the Incidence of Atrial Fibrillation Following Hospitalization for coronary artery disease. Europace. 2012 Sep;14(9):1287-93

 

Thai WE, Wai B, Lin K, Cheng T, Heist EK, Hoffmann U, Singh JP, Truong QA. Pulmonary Venous Anatomy Imaging with Low-Dose, Prospectively ECG-Triggered, High-Pitch 128-Slice Dual Source Computed Tomography. Circ Arrhythm Electrophysiol. 2012 Jun 1;5(3):521-30.

 

Chatterjee NA, Upadhyay GA, Ellenbogen KA, Hayes D, Singh JP. AV Nodal ablation in Atrial Fibrillation. A comparison of Biventricular vs. right ventricular pacing mode. Eur J Heart Fail. 2012 Jun;14(6):661-7.

 

Shah RV, Altman RK, Park MY, Zilinski J, Leyton-Mange J, Orencole M, Picard MH, Barrett CD, Heist EK, Upadhyay G, Das R, Singh JP, Das S. Usefulness of hemoglobin A(1c) to predict outcome after cardiac resynchronization therapy in patients with diabetes mellitus and heart failure. Am J Cardiol. 2012 Sep1;110(5):683-8. 

 

Altman RK, Parks KA, Schlett CL, Orencole M, Park MY, Truong QA, Deeprasertkul P, Moore SA, Barrett CD, Lewis GD, Das S, Upadhyay GA, Heist EK, Picard MH, Singh JP. Multidisciplinary care of patients receiving cardiac resynchronization therapy is associated with improved clinical outcomes. Eur Heart J. 2012 Sep;33(17):2181-8. 

 

Friedman DJ, Altman RK, Orencole M, Picard MH, Ruskin JN, Singh JP, Heist EK.  Predictors of sustained ventricular arrhythmias in cardiac resynchronization therapy. Circ Arrhythm Electrophysiol. 2012 Aug 1;5(4):762-72. 

 

Park MY, Altman RK, Orencole M, Kumar P, Parks KA, Heist KE, Singh JP, Picard MH. Characteristics of Responders to Cardiac Resynchronization Therapy: The Impact of Echocardiographic Left Ventricular Volume. Clin Cardiol. Clin Cardiol. 2012 Dec;35(12):777-80

 

Shetty AK, Duckett SG, Ginks MR, Ma Y, Sohal M, Bostock J, Kapetanakis S, Singh JP, Rhode K, Wright M, O'Neill MD, Gill JS, Carr-White G, Razavi R, Rinaldi CA. Cardiac magnetic resonance-derived anatomy, scar, and dyssynchrony fused with fluoroscopy to guide LV lead placement in cardiac resynchronization therapy: a comparison with acute haemodynamic measures and echocardiographic reverse remodelling. Eur Heart J Cardiovasc Imaging. Eur Heart J Cardiovasc Imaging. 2013 Jul;14(7):692-9..

 

Kron J, Sauer W, Schuller J, Bogun F, Crawford T, Sarsam S, Rosenfeld L, Mitiku TY, Cooper JM, Mehta D, Greenspon AJ, Ortman M, Delurgio DB, Valadri R, Narasimhan C, Swapna N, Singh JP, Danik S, Markowitz SM, Almquist AK, Krahn AD,Wolfe LG, Feinstein S, Ellenbogen KA. Efficacy and safety of implantable cardiac  defibrillators for treatment of ventricular arrhythmias in patients with cardiac sarcoidosis. Europace. 2013 Mar;15(3):347-54.

 

Kandala J, Upadhyay GA, Altman RK, Bose A, Heist EK, Mela T, Singh JP. Electrical Delay in Apically Positioned Left Ventricular Leads and Clinical Outcome After Cardiac Resynchronization Therapy. J Cardiovasc Electrophysiol. 2013:24:182-7.

 

Kumar P, Upadhyay GS, cavaliere-Ogus C, Heist EK, Altman RK, Chatterjee NA, Parks KA and Singh JP. Right Ventricular Lead Adjustment in Cardiac Resynchronization Therapy and Acute Hemodynamic Response: A Pilot Study. Journal Interventional Cardiovascular Electrophysiology, 2013: 36:223-31.

 

Friedman DJ, Upadhyay GA, Altman RK, Orencole M, Barrett CD, Mela T, Heist EK, Singh JP. The Anatomical and Electrical Location of the Left Ventricular Lead Predicts Ventricular Arrhythmia in Cardiac Resynchronization Therapy, Heart Rhythm 2013; 10: 668-75.

 

Armoundas AA, Weiss EH, Sayadi O, Laferriere S, Sajja N, Mela T, Singh JP, Barrett CD, Kevin Heist E, Merchant FM. Novel Pacing Method to Suppress Repolarization Alternans in Vivo: Implications for Arrhythmia Prevention. Heart Rhythm. 2013 Apr;10(4):564-72.

 

Gold MR, Yu Y, Singh JP, Stein KM, Birgersdotter-Green U, Meyer TE, Seth M, Ellenbogen KA.The Effect of Left Ventricular Electrical Delay on AV Optimization for Cardiac Resynchronization Therapy.  Heart Rhythm. 2013 Mar 11 (Epub ahead of print, PMID: 23499621).

 

Kandala J, Upadhyay GA, Wu S, Pokushalov E, Drachman D, Singh JP. Meta-Analysis Stem Cell Therapy in Chronic Ischemic Cardiomyopathy: A Meta-Analysis American Journal of Cardiology, 2013; Jul 15;112(2):217-25. 

 

Kandala J, Upadhyay GA, Orencole MA, Parks KA, Mela T, Heist EK, Singh JP. QRS Morphology, Left ventricular lead location and clinical outcome in patients receiving cardiac resynchronization therapy. European Heart Journal 2013 Aug; 34(29):2252-62.

 

Singh JP, Abraham WT, Chung ES, RogersT, Sambelashvilli A, Coles JA, Martin DO. Clinical Response with Adaptive CRT Algorithm Compared to CRT with Echocardiography-Optimized Atrioventricular Delay: A Retrospective Analysis of Multicenter Trials. Europace 2013 Nov;15(11):1622-8

 

Friedman DJ, Upadhyay GA, Singal G, Orencole M, Moore SA, Parks KA, Heist EK, Singh JP. Usefulness and Consequences of Cardiac Resynchronization Therapy in Dialysis Dependent Patients with Heart Failure. Am J Cardiol. 2013 Nov 15;112(10):1625-31

 

Ruschitzka F,* Abraham WT,* Singh JP*, Bax JJ, Borer JS, Brugada J, DicksteinK, Ford I, Gorscan J, Gras D, Krum H, Sogaard P, Holzmeister J* for the EchoCRT Study Group. EchoCRT: Echocardiographic guided Cardiac Resynchronization Therapy in patients with symptomatic heart failure and narrow QRS complex.  N Engl J Med. 2013 Oct 10; 369(15):1395-405. (*equal contribution)

 

Bose A, Kandala J, Upadhyay GA, Riedl L, ahmado I, Padmanabhan, Gewirtz G, Mulligan LJ, Singh JP. Impact of Myocardial Viability and Left Ventricular Lead location on Clinical Outcome in Cardiac Resynchronization Therapy Recipients with Ischemic Cardiomyopathy.  J Cardiovasc Electrophysiol 2014 May;25(5):507-13.

 

Koci F, Forbes P, Mansour MC, Heist EK, Singh JP, Ellinor PT, Ruskin JN. New Classification Scheme for Atrial Fibrillation Symptom Severity and Burden. Am J Cardiol. 2014 Jul 15;114(2):260-5.

 

Sharma AK, Vegh EM, Kandala J, Orencole M, Januszkiewicz L, Bose A, Miller A, Parks KA, Heist EK, Singh JP. Usefulness of Hyponatremia as a Predictor for Adverse Events in Patients With Heart Failure Receiving Cardiac Resynchronization Therapy. Am J Cardiol. 2014 Jul 1;114(1):83-7. 

 

Bose A, Upadhyay GA, Kandala J, Heist EK, Mela T, Parks K, Singh JP. Does Prior Valve Surgery Change Outcome in Patients Treated with Cardiac Resynchronization Therapy? J Cardiovasc Electrophysiol. 2014 Nov;25(11):1206-1. PMID: 24903306

 

Vegh EM, Kandala J, Orencole M, Upadhyay GA, Sharma A, Miller A, Merkely B, Parks KA, Singh JP. Device-measured physical activity versus six-minute walk test as a predictor of reverse remodeling and outcome after cardiac resynchronization therapy for heart failure. Am J Cardiol. 2014  1;113(9):1523-8.

 

Brugada J, Brachmann J, Delnoy PP, Padeletti L, Reynolds D, Ritter P, Borri-Brunetto A, Singh JP. Automatic Optimization of Cardiac Resynchronization Therapy Using SonR– Rationale and Design of the RESPOND CRT Trial. American Heart Journal 2014;167(4):429-36.

 

Chatterjee NA, Upadhyay GA, Singal G, Parks KA, Dec GW, Singh JP, Lewis GD.  Pre-capillary pulmonary hypertension and right ventricular dilation predict clinical outcome in cardiac resynchronization therapy. JACC Heart Fail.  2014 Jun;2(3):230-7. PMID: 24952689

 

Engels, E; Vegh, EM ; van Deursen, C; Vernooy, K; Singh, JP; Prinzen, F.  T-wave area predicts response to cardiac resynchronization therapy in patients with left bundle branch block. J Cardiovasc Electrophysiol  2014 (PMID: 25230363)

 

Truong QA, Januzzi JL, Szymonifka J, Thai WE, Wai B, Lavender Z, Sharma U, Sandoval RM, Grunau ZS, Basnet S, Babatunde A, Ajijola OA, Min JK, Singh JP. Coronary sinus biomarker sampling compared to peripheral venous blood for predicting outcomes in patients with severe heart failure undergoing cardiac resynchronization therapy: The BIOCRT study. Heart Rhythm. Heart Rhythm. 2014 Dec;11(12):2167-75. 

 

Acha MR, Keaney JJ, Lubitz SA, Milan DJ, Mansour M, E Heist K, Ptaszek LM, Singh JP, Blendea D, Mela T. Increased Perforation Risk with an MRI-Conditional Pacing Lead: A Single-Center Study. Pacing Clin Electrophysiol. 2015 Mar;38(3):334-42.

 

Sayadi O, Puppala D, Ishaque N, Doddamani R, Merchant FM, Barrett C, Singh JP, Heist EK, Mela T, Martínez JP, Laguna P, Armoundas AA. A novel method to capture the onset of dynamic electrocardiographic ischemic changes and its implications to arrhythmia susceptibility. J Am Heart Assoc. 2014 Sep 3; PMID: 25187521. 

 

Friedman DJ, Upadhyay GA, Rajabali A, Altman RK, Orencole M, Parks KA, Moore SA, Park MY, Picard MH, Ruskin JN, Singh JP, Heist EK. Progressive ventricular dysfunction among non-responders to cardiac resynchronization therapy: Baseline predictors and associated clinical outcome Heart Rhythm. 2014 Nov;11(11):1991-8. 

 

Sharma AK, Vegh E, Orencole M, Miller A, Blendea D, Moore S, Lewis GD, Singh JP, Parks KA, Heist EK. Association of hypothyroidism with adverse events in patients with heart failure receiving cardiac resynchronization therapy. Am J Cardiol. 2015 May 1;115(9):1249-53. 

 

Upadhyay GA, Chatterjee NA, Kandala J, Friedman DJ, Park MY, Tabtabai SR, Hung J, Singh JP. Assessing mitral regurgitation in the prediction of clinical outcome after cardiac resynchronization therapy. Heart Rhythm. 2015 Jun;12(6):1201-8. 

 

Shalaby AA, Abraham WT, Fonarow GC, Bersohn MM, Gorcsan J 3rd, Lee LY, Halilovic J, Saba S, Maisel A, Singh JP, Sonel A, Kadish A. Association of BNP and Troponin Levels with Outcome among Cardiac Resynchronization Therapy Recipients. Pacing Clin Electrophysiol. 2015 May;38(5):581-90. 

 

Kron J, Sauer W, Mueller G, Schuller J, Bogun F, Sarsam S, Rosenfeld L, Mitiku TY, Cooper JM, Mehta D, Greenspon AJ, Ortman M, Delurgio DB, Valadri R, Narasimhan C, Swapna N, Singh JP, Danik S, Markowitz SM, Almquist AK, Krahn AD, Wolfe LG, Feinstein S, Ellenbogen KA, Crawford T. Outcomes of patients with definite and suspected isolated cardiac sarcoidosis treated with an implantable cardiac defibrillator. J Interv Card Electrophysiol. 2015 Jun;43(1):55-64.

 

Maurer MS, Adamson PB, Costanzo MR, Eigler N, Gilbert J, Gold MR, Klapholz M, Saxon LA, Singh JP, Troughton R, Abraham WT. Rationale and Design of the Left Atrial Pressure Monitoring to Optimize Heart Failure Therapy Study (LAPTOP-HF). J Card Fail. 2015 Jun;21(6):479-88.

 

Januszkiewicz Ł, Vegh E, Rasmus B, Bose A, Sharma A, Orencole M, Mela T, Singh JP, Parks KA. Prognostic Implication of Baseline Pr Interval in Cardiac Resynchronization Therapy Recipients. Heart Rhythm. 2015, Nov;12(11):2256-62. 

 

Steffel J, Robertson M, Singh JP, Abraham WT, Bax JJ, Borer JS, Dickstein K, Ford I, Gorcsan J 3rd, Gras D, Krum H, Sogaard P, Holzmeister J, Brugada J, Ruschitzka F The effect of QRS duration on cardiac resynchronization therapy in patients with a narrow QRS complex: a subgroup analysis of the EchoCRT trial. Eur Heart J. 2015 May 25; PMID: 26009595 

 

Melman YF, Shah R, Danielson K, Xiao J, Simonson B, Barth A, Chakir K, Lavender Z, Lewis GD, Truong QA, Kleber A, Das R, Rosenzweig A, Wang Y, Kass D, Singh JP, Das S. Circulating MicroRNA-30d is Associated with Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study. Circulation. 2015 May 20.. [Epub ahead of print] PMID: 25995320. 

 

Truong QA, Thai WE, Wai B, Cordaro K, Cheng T, Beaudoin J, Xiong G, Cheung JW, Altman R, Min JK, Singh JP, Barrett CD, Danik S. Myocardial scar imaging by standard single-energy and dual-energy late enhancement CT: Comparison with pathology and electroanatomic map in an experimental chronic infarct porcine model. J Cardiovasc Comput Tomogr. 2015 Mar 24. [Epub ahead of print], PMID: 25977115 

 

Engels EB, Végh EM, Van Deursen CJ, Vernooy K, Singh JP, Prinzen FW.T-wave area predicts response to cardiac resynchronization therapy in patients with left bundle branch block. J Cardiovasc Electrophysiol. 2015 Feb;26(2):176-83. 

 

Tereshchenko LG, Cheng A, Park J, Wold N, Meyer TE, Gold MR, Mittal S, Singh JP, Stein KM, Ellenbogen KA; SMART-AV Trial Investigators. Novel measure of electrical dyssynchrony predicts response in cardiac resynchronization therapy: Results from the SMART-AV Trial. Heart Rhythm. 2015 Dec;12(12):2402-10.

 

Sayadi O, Puppala D, Ishaque N, Doddamani R, Merchant FM, Barrett C, Singh JP, Heist EK, Mela T, Martínez JP, Laguna P, Armoundas AA. A novel method to capture the onset of dynamic electrocardiographic ischemic changes and its implications to arrhythmia susceptibility. J Am Heart Assoc. 2014 Sep 3;3(5):e001055. PMID: 251875

 

Singal G, Upadhyay GA, Borgquist R, Friedman DJ, Chatterjee NA, Kandala J, Park MY, Orencole M, Dec GW, Picard MH, Singh JP, Mela T. Renal Response in Patients with Chronic Kidney Disease Predicts Outcome Following Cardiac Resynchronization Therapy. Pacing Clin Electrophysiol. 2015 Oct;38(10):1192-200. 

 

Chatterjee NA, Roka A, Lubitz SA, Gold MR, Daubert C, Linde C, Steffel J, Singh JP, Mela T. Reduced appropriate implantable cardioverter-defibrillator therapy after cardiac resynchronization therapy-induced left ventricular function recovery: a meta-analysis and systematic review. Eur Heart J. 2015 Nov1;36(41):2780-9. 

 

Niazi IK, Sperzel J, Heist EK, Rosenberg SP, Ryu K, Yang M, D'Avila A, Singh JP. Three-Dimensional Cardiac Mapping Characterizes Ventricular Contractile Patterns during Cardiac Resynchronization Therapy Implant: A Feasibility Study. Pacing Clin Electrophysiol. 2015 Sep;38(9):1091-8.

 

Steffel J, Varma N, Robertson M, Singh JP, Bax JJ, Borer JS, Dickstein K, Ford I, Gorcsan J 3rd, Gras D, Krum H, Sogaard P, Holzmeister J, Brugada J, Abraham WT, Ruschitzka F. Effect of Gender on Outcomes After Cardiac Resynchronization Therapy in Patients With a Narrow QRS Complex: A Subgroup Analysis of the EchoCRT rial. Circ Arrhythm Electrophysiol. 2016 Jun;9(6). pii: e003924. doi:10.1161/CIRCEP.115.003924. PubMed PMID: 27282848

2016 - present

Januszkiewicz Ł, Vegh E, Borgquist R, Bose A, Sharma A, Orencole M, Mela T, Singh JP, Parks KA. Reply to the Editor-Prognostic Implication of Baseline PR Interval in Patients Undergoing Cardiac Resynchronization Therapy. Heart Rhythm. 2016 Jul;13(7):1573-4. 

 

Jacobsson J, Borgquist R, Reitan C, Ghafoori E, Chatterjee NA, Kabir M, Platonov PG, Carlson J, Singh JP, Tereshchenko LG. Usefulness of the Sum Absolute QRST Integral to Predict Outcomes in Patients Receiving Cardiac Resynchronization Therapy. Am J Cardiol. 2016 Aug 1;118(3):389-95. doi: 10.1016/j.amjcard.2016.05.017. Epub 2016 May 14. PubMed PMID: 27265674; PubMed Central PMCID: PMC4958489

Belperio J, Horwich T, Abraham WT, Fonarow GC, Gorcsan J 3rd, Bersohn MM, Singh JP, Sonel A, Lee LY, Halilovic J, Kadish A, Shalaby AA. Inflammatory Mediators and Clinical Outcome in Patients With Advanced Heart Failure Receiving Cardiac Resynchronization Therapy. Am J Cardiol. 2016 Feb 15;117(4):617-25.

 

Chatterjee NA, Singh JP, Szymonifka J, Deaño RC, Thai WE, Wai B, Min JK, Januzzi JL, Truong QA. Incremental value of cystatin C over conventional renal metrics for predicting clinical response and outcomes in cardiac resynchronization therapy: The BIOCRT study. Int J Cardiol. 2016: 15;205:43-9.

 

Végh EM, Engels EB, van Deursen CJ, Merkely B, Vernooy K, Singh JP, Prinzen FW. T-wave area as biomarker of clinical response to cardiac resynchronization therapy. Europace. 2016 Jul;18(7):1077-85.

 

Venkateswaran RV, Freeman C, Chatterjee N, Kandala J, Orencole M, Vegh EM, Parks KA, Cowburn PJ, Dec GW, Singh JP, Borgquist R. Anemia and its association with clinical outcome in heart failure patients undergoing cardiac resynchronization therapy. J Interv Card Electrophysiol. 2015 Dec;44(3):297-304.

 

Friedman DJ, Singh JP, Curtis JP, Tang WH, Bao H, Spatz ES, Hernandez AF, Patel UD, Al-Khatib SM. Comparative Effectiveness of CRT-D Versus Defibrillator Alone in HF Patients With Moderate-to-Severe Chronic Kidney Disease. J Am Coll Cardiol. 2015 Dec 15;66(23-30). 

 

Perrotta L, Kandala J, DI Biase L, Valleggi A, Michelotti F, Pieragnoli P, Ricciardi G, Mascioli G, Lakkireddy D, Pillarisetti J, Emdin M, Natale A, Singh JP, Padeletti L. Prognostic Impact of QRS Axis Deviation in Patients Treated With Cardiac Resynchronization Therapy. J Cardiovasc Electrophysiol. 2016 Mar;27(3):315-20. 

 

Lindvall C, Chatterjee NA, Chang Y, Chernack B, Jackson VA, Singh JP, Metlay JP. National Trends in the Use of Cardiac Resynchronization Therapy With or Without Implantable Cardioverter-Defibrillator. Circulation. 2016 Jan 19;133(3):273-81.

 

Gorcsan J 3rd, Sogaard P, Bax JJ, Singh JP, Abraham WT, Borer JS, Dickstein K, Gras D, Krum H, Brugada J, Robertson M, Ford I, Holzmeister J, Ruschitzka F. Association of persistent or worsened echocardiographic dyssynchrony with unfavourable clinical outcomes in heart failure patients with narrow QRS width: a subgroup analysis of the EchoCRT trial. Eur Heart J. 2016 Jan 1;37(1):49-59.

 

Beaudoin J, Singh JP, Szymonifka J, Zhou Q, Levine RA, Januzzi JL, Truong QA. Novel Heart Failure Biomarkers Predict Improvement of Mitral Regurgitation in Patients Receiving Cardiac Resynchronization Therapy-The BIOCRT Study. Can J Cardiol. 2016 Dec;32(12):1478-1484. 

 

Hummel JD, Coppess MA, Osborn JS, Yee R, Fung JW, Augostini R, Li S, Hine D, Singh JP. Real-World Assessment of Acute Left Ventricular Lead Implant Success and Complication Rates: Results from the Attain Success Clinical Trial. Pacing Clin Electrophysiol. 2016 Nov;39(11):1246-1253. 

 

Chatterjee NA, Gold MR, Waggoner AD, Picard MH, Stein KM, Yu Y, Meyer TE, Wold N, Ellenbogen KA, Singh JP. Longer Left Ventricular Electric Delay Reduces Mitral Regurgitation After Cardiac Resynchronization Therapy: Mechanistic Insights From the SMART-AV Study (SmartDelay Determined AV Optimization: A Comparison to Other AV Delay Methods Used in Cardiac Resynchronization Therapy). Circ Arrhythm Electrophysiol. 2016 Nov;9(11). 

 

Kutyifa V, Beck C, Brown MW, Cannom D, Daubert J, Estes M, Greenberg H, Goldenberg I, Hammes S, Huang D, Klein H, Knops R, Kosiborod M, Poole J, Schuger C, Singh JP, Solomon S, Wilber D, Zareba W, Moss AJ; MADIT S-ICD Executive Committee. Multicenter Automatic Defibrillator Implantation Trial-Subcutaneous Implantable Cardioverter Defibrillator (MADIT S-ICD): Design and clinical protocol. Am Heart J. 2017 Jul;189:158-166. doi: 10.1016/j.ahj.2017.04.014. 

 

Bax JJ, Delgado V, Sogaard P, Singh JP, Abraham WT, Borer JS, Dickstein K, Gras D, Brugada J, Robertson M, Ford I, Krum H, Holzmeister J, Ruschitzka F, Gorcsan J. Prognostic implications of left ventricular global longitudinal strain in heart failure patients with narrow QRS complex treated with cardiac resynchronization therapy: a subanalysis of the randomized EchoCRT trial. Eur Heart J. 2017 Mar 7;38(10):720-726.  

 

Sohn K, Merchant FM, Sayadi O, Puppala D, Doddamani R, Sahani A, Singh JP, Heist EK, Isselbacher EM, Armoundas AA. A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems. Sci Rep. 2017 Mar 22;7:44946. 

 

Boehmer JP, Hariharan R, Devecchi FG, Smith AL, Molon G, Capucci A, An Q, Averina V, Stolen CM, Thakur PH, Thompson JA, Wariar R, Zhang Y, Singh JP. A Multisensor Algorithm Predicts Heart Failure Events in Patients With Implanted Devices: Results From the MultiSENSE Study. JACC Heart Fail. 2017 Mar;5(3):216-225.

 

Végh EM, Kandala J, Januszkiewicz L, Ren J, Miller A, Orencole M, Blendea D, Merkely B, Gellér L, Singh JP, Borgquist R. A new simplified electrocardiographic score predicts clinical outcome in patients treated with CRT. Europace. 2018 Mar 1;20(3):492-50010.1093

 

Arrigo M, Truong QA, Szymonifka J, Rivas-Lasarte M, Tolppanen H, Sadoune M, Gayat E, Cohen-Solal A, Ruschitzka F, Januzzi JL Jr, Singh JP, Mebazaa A. Mid-regional pro-atrial natriuretic peptide to predict clinical course in heart failure patients undergoing cardiac resynchronization therapy. Europace. 2017 Nov 1;19(11):1848-1854. 

 

Nägele MP, Steffel J, Robertson M, Singh JP, Flammer AJ, Bax JJ, Borer JS, Dickstein K, Ford I, Gorcsan J 3rd, Gras D, Krum H, Sogaard P, Holzmeister J, Abraham WT, Brugada J, Ruschitzka F.  Effect of cardiac resynchronization therapy in patients with diabetes randomized in EchoCRT. Eur J Heart Fail. 2017 Jan;19(1):80-87. 

 

Arrigo M, Truong QA, Onat D, Szymonifka J, Gayat E, Tolppanen H, Sadoune M, Demmer RT, Wong KY, Launay JM, Samuel JL, Cohen-Solal A, Januzzi JL Jr, Singh JP, Colombo PC, Mebazaa A. Soluble CD146 Is a Novel Marker of Systemic Congestion in Heart Failure Patients: An Experimental Mechanistic and Transcardiac Clinical Study. Clin Chem. 2017 Jan;63(1):386-393.

 

Chatterjee NA, Borgquist R, Chang Y, Lewey J, Jackson VA, Singh JP, Metlay JP, Lindvall C. Increasing sex differences in the use of cardiac resynchronization therapy with or without implantable cardioverter-defibrillator. Eur Heart J. 2017 May 14;38(19):1485-1494. 

 

Brugada J, Delnoy PP, Brachmann J, Reynolds D, Padeletti L, Noelker G, Kantipudi C, Rubin Lopez JM, Dichtl W, Borri-Brunetto A, Verhees L, Ritter P, Singh JP. Contractility sensor-guided optimization of cardiac resynchronization therapy: results from the RESPOND-CRT trial.

Eur Heart J. 2017 Mar 7;38(10):730-738. 

 

Mihos CG, Yucel E, Capoulade R, Orencole MP, Upadhyay GA, Santana O, Singh JP, Picard MH. Impact of cardiac resynchronization therapy on mitral valve apparatus geometry and clinical outcomes in patients with secondary mitral regurgitation. Echocardiography. 2017 Nov;34(11):1561-1567. 

 

Kutyifa V, Beck C, Brown MW, Cannom D, Daubert J, Estes M, Greenberg H, Goldenberg I, Hammes S, Huang D, Klein H, Knops R, Kosiborod M, Poole J, Schuger C, Singh JP, Solomon S, Wilber D, Zareba W, Moss AJ; MADIT S-ICD Executive Committee. Multicenter Automatic Defibrillator Implantation Trial-Subcutaneous Implantable Cardioverter Defibrillator (MADIT S-ICD): Design and clinical protocol. Am Heart J. 2017 Jul;189:158-166. 

 

Boehmer JP, Hariharan R, Devecchi FG, Smith AL, Molon G, Capucci A, An Q, Averina V, Stolen CM, Thakur PH, Thompson JA, Wariar R, Zhang Y, Singh JP. A Multisensor Algorithm Predicts Heart Failure Events in Patients With Implanted Devices: Results From the MultiSENSE Study. JACC Heart Fail. 2017 Mar;5(3):216-225.

 

Sohn K, Merchant FM, Sayadi O, Puppala D, Doddamani R, Sahani A, Singh JP, Heist EK, Isselbacher EM, Armoundas AA. A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems. Sci Rep. 2017 Mar 22;7:44946.

 

Truong QA, Szymonifka J, Picard MH, Thai WE, Wai B, Cheung JW, Heist EK, Hoffmann U, Singh JP. Utility of dual-source computed tomography in cardiac resynchronization therapy-DIRECT study. Heart Rhythm. 2018 Aug;15(8):1206-1213. 

 

Oesterle A, Weber B, Tung R, Choudhry NK, Singh JP, Upadhyay GA. Preventing Postoperative Atrial Fibrillation After Noncardiac Surgery: A Meta-analysis. Am J Med. 2018 Jul;131(7):795-804.

 

Gardner RS, Singh JP, Stancak B, Nair DG, Cao M, Schulze C, Thakur PH, An Q, Wehrenberg S, Hammill EF, Zhang Y, Boehmer JP. HeartLogic Multisensor Algorithm Identifies Patients During Periods of Significantly Increased Risk of Heart Failure Events: Results From the MultiSENSE Study. Circ Heart Fail. 2018 Jul;11(7):e004669.

 

Lercher P, Lunati M, Rordorf R, Landolina M, Badie N, Qu F, Casset C, Ryu K, Ghio S, Singh JP, Leclercq C. Long-term reverse remodeling by cardiac resynchronization therapy with MultiPoint Pacing: A feasibility study of noninvasive hemodynamics-guided device programming. Heart Rhythm. 2018 Jun 22. S1547-5271(18)30610-6.

 

Varma N, Sogaard P, Bax JJ, Abraham WT, Borer JS, Dickstein K, Singh JP, Gras D, Holzmeister J, Brugada J, Ruschitzka F. Interaction of Left Ventricular Size and Sex on Outcome of Cardiac Resynchronization Therapy Among Patients With a Narrow QRS Duration in the EchoCRT Trial. J Am Heart Assoc. 2018 May 27;7(11).

 

Arrigo M, Vodovar N, Nougué H, Sadoune M, Pemberton CJ, Ballan P, Ludes PO, Gendron N, Carpentier A, Cholley B, Bizouarn P, Cohen-Solal A, Singh JP, Szymonifka J, Latremouille C, Samuel JL, Launay JM, Pottecher J, Richards AM, Truong QA, Smadja DM, Mebazaa A. The heart regulates the endocrine response to heart failure: cardiac contribution to circulating neprilysin. Eur Heart J. 2018 May 21;39(20):1794-1798. 

 

Bakos Z, Chatterjee NC, Reitan C, Singh JP, Borgquist R. Prediction of clinical outcome in patients treated with cardiac resynchronization therapy – the role of NT-ProBNP and a combined response score. BMC Cardiovasc Disord. 2018 Apr 24;18(1):70. 

 

Tayal B, Gorcsan J 3rd, Bax JJ, Risum N, Olsen NT, Singh JP, Abraham WT, Borer JS, Dickstein K, Gras D, Krum H, Brugada J, Robertson M, Ford I, Holzmeister J, Ruschitzka F, Sogaard P. Cardiac Resynchronization Therapy in Patients With Heart Failure and Narrow QRS Complexes. J Am Coll Cardiol. 2018 Mar 27;71(12):1325-1333. 

 

Belkin MN, Soria CE, Waldo AL, Borleffs CJW, Hayes DL, Tung R, Singh JP, Upadhyay GA. Incidence and Clinical Significance of New-Onset Device-Detected Atrial Tachyarrhythmia: A Meta-Analysis. Circ Arrhythm Electrophysiol. 2018 Mar;11(3):e005393. doi: 10.1161/CIRCEP.117.005393. PubMed PMID: 29540371.

 

Mihos CG, Yucel E, Capoulade R, Orencole MP, Upadhyay GA, Santana O, Singh JP, Picard MH. Effects of cardiac resynchronization therapy after inferior myocardial infarction on secondary mitral regurgitation and mitral valve geometry. Pacing Clin Electrophysiol. 2018 Feb;41(2):114-121. 

 

Singh JP, Berger RD, Doshi RN, Lloyd M, Moore D, Daoud EG; ENHANCE CRT Study Group Rationale and design for ENHANCE CRT: QLV implant strategy for non-left bundle branch block patients. ESC Heart Fail. 2018 Sep 27. doi:10.1002/ehf2.12340. [Epub ahead of print] PubMed PMID: 30264456.

 

Gold MR, Yu Y, Singh JP, Birgersdotter-Green U, Stein KM, Wold N, Meyer TE, Ellenbogen KA. Effect of Interventricular Electrical Delay on Atrioventricular Optimization for Cardiac Resynchronization Therapy. Circ Arrhythm Electrophysiol. 2018 Aug;11(8):e006055. 

 

Truong QA, Szymonifka J, Januzzi JL, Contractor JH, Deaño RC, Chatterjee NA, Singh JP. Cardiorenal status using amino-terminal pro-brain natriuretic peptide and cystatin C on cardiac resynchronization therapy outcomes: From the BIOCRT Study. Heart Rhythm. 2018 Dec 24. pii: S1547-5271(18)31289-X. doi: 10.1016/j.hrthm.2018.12.023. [Epub ahead of print] PubMed PMID: 30590191.

 

Kutyifa V, Kosztin A, Klein HU, Biton Y, Nagy VK, Solomon SD, McNitt S, Zareba W, Goldenberg I, Roka A, Moss AJ, Merkely B, Singh JP. Left Ventricular Lead Location and Long-Term Outcomes in Cardiac Resynchronization Therapy Patients. JACC Clin Electrophysiol. 2018 Nov;4(11):1410-1420. Doi: 10.1016/j.jacep.2018.07.006. Epub 2018 Aug 29. PubMed PMID: 30466845.

 

Martin LM, Januzzi JL Jr, Thompson RW, Ferris TG, Singh JP, Bhambhani V, Wasfy JH.Clinical Profile of Acute Myocardial Infarction Patients Included in the Hospital Readmissions Reduction Program. J Am Heart Assoc. 2018 Aug 21;7(16):e009339. doi: 10.1161/JAHA.118.009339. PubMed PMID: 30369306; PubMed Central PMCID: PMC6201407.

 

Normand C, Linde C, Singh JP, Dickstein K. Indications for Cardiac Resynchronization Therapy: A Comparison of the Major International Guidelines. JACC Heart Fail. 2018 Apr;6(4):308-316. 

 

Butala NM, Hidrue MK, Swersey AJ, Singh JP, Weilburg JB, Ferris TG, Armstrong KA, Wasfy JH. Measuring individual physician clinical productivity in an era of consolidated group practices. Healthc (Amst). 2019 Feb 8. pii:S2213-0764(18)30051-4. doi: 10.1016/j.hjdsi.2019.02.001. PubMed PMID: 30744992.

 

Truong QA, Szymonifka J, Januzzi JL, Contractor JH, Deaño RC, Chatterjee NA, Singh JP. Cardiorenal status using amino-terminal pro-brain natriuretic peptide and cystatin C on cardiac resynchronization therapy outcomes: From the BIOCRT Study. Heart Rhythm. 2019 Jun;16(6):928-935.

 

Kulkarni K, Merchant FM, Kassab MB, Sana F, Moazzami K, Sayadi O, Singh JP, Heist EK, Armoundas AA. Cardiac Alternans: Mechanisms and Clinical Utility in Arrhythmia Prevention. J Am Heart Assoc. 2019 Nov 5;8(21):e013750. 

 

Sohn K, Dalvin SP, Merchant FM, Kulkarni K, Sana F, Abohashem S, Singh JP, Heist EK, Owen C, Isselbacher EM, Armoundas AA. Utility of a Smartphone Based System (cvrPhone) to Predict Short-term Arrhythmia Susceptibility. Sci Rep. 2019 Oct 10;9(1):14497. 

 

Singh JP, Abraham WT, Auricchio A, Delnoy PP, Gold M, Reddy VY, Sanders P, Lindenfeld J, Rinaldi CA. Design and rationale for the Stimulation Of the Left Ventricular Endocardium for Cardiac Resynchronization Therapy in non-responders and previously untreatable patients (SOLVE-CRT) trial. Am Heart J. 2019 Apr 9;217:13-22. 

 

Galand V, Ghoshhajra B, Szymonifka J, Leclercq C, Truong QA, Singh JP. Computed Tomography-Guided Assessment of Response to Cardiac Resynchronization Therapy. JACC Clin Electrophysiol. 2019 Aug;5(8):987-989.

 

Mihos CG, Santana O, Yucel E, Capoulade R, Upadhyay GA, Orencole MP, Singh JP, Picard MH. The effects of cardiac resynchronization therapy on left ventricular and mitral valve geometry and secondary mitral regurgitation in patients with left bundle branch block. Echocardiography. 2019 Aug;36(8):1450-1458. 

 

Sohn K, Merchant FM, Abohashem S, Kulkarni K, Singh JP, Heist EK, Owen C, Roberts JD Jr, Isselbacher EM, Sana F, Armoundas AA. Utility of a smartphone based system (cvrphone) to accurately determine apneic events from electrocardiographic signals. PLoS One. 2019 Jun 17;14(6):e0217217. 

 

Friedman DJ, Pokorney SD, Khanna R, Goldstein L, Atwater BD, Bahnson TD, Daubert JP, Jackson KP, Heist EK, Singh JP, Calkins H, Piccini JP. Catheter Ablation of Atrial Fibrillation With and Without On-Site Cardiothoracic Surgery. J Am Coll Cardiol. 2019 May 21;73(19):2487-2489.

 

Ajijola OA, Chatterjee NA, Gonzales MJ,  Gornbein J, Liu K, Li D, Paterson DJ, Shivkumar K, Singh JP, Herring N. Coronary sinus Neuropeptide-Y levels predict adverse outcomes in patients with stable chronic heart failure. JAMA Cardiology, 2020 JAMA Cardiol. 2020 Mar 1;5(3):318-325

 

Singh JP, Solomon SD, Fradley MG, Barac, A; Kremer KA; Beck CA,  Brown MA; McNitt S,
Schleede, S; Zareba W, ; Goldenberg I; Kutyifa V; for the MADIT-CHIC Investigators. Association of Cardiac Resynchronization Therapy With Change in Left Ventricular Ejection Fraction in Patients With Chemotherapy-Induced Cardiomyopathy. JAMA,. 2019 Nov 12;322(18):1799-1805. 

 

Wasfy JH, Hidrue MK, Ngo J, Tanguturi VK, Cafiero-Fonseca ET, Thompson RW, Johnson N, McDermott ST, Singh JP, Del Carmen MG, Ferris TG. Association of an Acute Myocardial Infarction Readmission-Reduction Program With Mortality and Readmission. Circ Cardiovasc Qual Outcomes. 2020 May;13(5):e00604

 

Singh JP, Cha YM, Lunati M, Chung ES, Li S, Smeets P, O'Donnell D. Real-world behavior of CRT pacing using the AdaptivCRT algorithm on patient outcomes: Effect on mortality and atrial fibrillation incidence. J Cardiovasc Electrophysiol. 2020 Apr;31(4):825-833

 

Merchant FM, Sayadi O, Sohn K, Weiss EH, Puppala D, Doddamani R, Singh JP, Heist EK, Owen C, Kulkarni K, Armoundas AA Real-Time Closed-Loop Suppression of Repolarization Alternans Reduces Arrhythmia Susceptibility In Vivo. Circ Arrhythm Electrophysiol. 2020 Jun;13(6):e008186 

 

Galand V, Ghoshhajra B, Szymonifka J, Das S, Orencole M, Barré V, Martins RP, Leclercq C, Hung J, Truong QA, Singh JP. Left ventricular wall thickness assessed by cardiac computed tomography and cardiac resynchronization therapy outcomes. Europace. 2020 Mar 1;22(3):401-411

 

Sharma A, Wu J, Xu H, Hernandez A, Felker GM, Al-Khatib S, Green J, Matsouaka R, Fonarow GC, Singh JP, Heidenreich PA, Ezekowitz JA, DeVore A Comparative Effectiveness of Primary Prevention Implantable Cardioverter-Defibrillators in Older Heart Failure Patients With Diabetes Mellitus. J Am Heart Assoc. 2020 Jun 16;9(12):e012405

 

Galand V, Ghoshhajra B, Szymonifka J, Das S, Leclercq C, Martins RP, Truong QA, Singh JPUtility of Computed Tomography to Predict Ventricular Arrhythmias in Patients With Nonischemic Cardiomyopathy Receiving Cardiac Resynchronization Therapy. Am J Cardiol. 2020 Feb 15;125(4):607

 

Mihos CG, Yucel E, Upadhyay GA, Orencole MP, Singh JP, Picard MH. Left ventricle and mitral valve reverse remodeling in response to cardiac resynchronization therapy in nonischemic cardiomyopathy. Echocardiography. 2020 Oct;37(10):1557-1565

 

Singh JP, Berger RD, Doshi RN, Lloyd M, Moore D, Stone J, Daoud EG; ENHANCE CRT Study Group. Targeted Left Ventricular Lead Implantation Strategy for Non-Left Bundle Branch Block Patients: The ENHANCE CRT Study. JACC Clin Electrophysiol. 2020 Sep;6(9):1171-1181.

 

Yuyun MF, Erqou SA, Peralta AO, Hoffmeister PS, Yarmohammadi H, Echouffo-Tcheugui JB, Martin DT, Joseph J, Singh JP. Ongoing Risk of Ventricular Arrhythmias and All-Cause Mortality at Implantable Cardioverter Defibrillator Generator Change: A Systematic Review and Meta-Analysis. Circ Arrhythm Electrophysiol. 2021 Mar;14(3):e009139

 

Maille B, Wilkin M, Million M, Rességuier N, Franceschi F, Koutbi-Franceschi L, Hourdain J, Martinez E, Zabern M, Gardella C, Tissot-Dupont H, Singh JP, Deharo JC, Fiorina L. Smartwatch Electrocardiogram and Artificial Intelligence for Assessing Cardiac-Rhythm Safety of Drug Therapy in the COVID-19 Pandemic. The QT-logs study. Int J Cardiol. 2021 May 15;331:333-339

 

Yuyun MF, Erqou SA, Peralta AO, Hoffmeister PS, Yarmohammadi H, Echouffo Tcheugui JB, Martin DT, Joseph J, Singh JP. Risk of ventricular arrhythmia in cardiac resynchronization therapy responders and super-responders: a systematic review and meta-analysis. Europace. 2021 Jan 26:euaa414. doi: 10.1093

 

Kemar, B, Mathenge N, Crousillat D, Singh JP, Bhatt A. Social determinants of telemedicine utilization in ambulatory cardiovascular patients during the COVID-19 pandemic. European Heart Journal-Digital Health (in press).

bottom of page